A randomised phase II trial of epirubicin and 5-fluorouracil versus cisplatinum in the palliation of advanced and recurrent malignant tumour of the salivary glands
- PMID: 7678976
- PMCID: PMC1968228
- DOI: 10.1038/bjc.1993.19
A randomised phase II trial of epirubicin and 5-fluorouracil versus cisplatinum in the palliation of advanced and recurrent malignant tumour of the salivary glands
Abstract
Sixteen patients with advanced and recurrent malignant salivary gland tumours were admitted to a randomised trial and the response assessed. Seven patients received Epirubicin/5-Fluorouracil and none of these patients responded. Nine patients received Cisplatinum and only one patient had a partial response. The trial suggests that chemotherapy has no place in the treatment of advanced salivary gland malignant tumours.
Comment in
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P-values, survival analyses and phase II trials.Br J Cancer. 1994 Jun;69(6):1182-3. doi: 10.1038/bjc.1994.232. Br J Cancer. 1994. PMID: 8043122 Free PMC article. No abstract available.
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