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Case Reports
. 1993 Feb;6(2):121-3.
doi: 10.1002/gcc.2870060210.

Rearrangement of band q13 on both chromosomes 12 in a periosteal chondroma

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Case Reports

Rearrangement of band q13 on both chromosomes 12 in a periosteal chondroma

N Mandahl et al. Genes Chromosomes Cancer. 1993 Feb.

Abstract

Cytogenetic analysis of a recurrent periosteal chondroma revealed nonreciprocal translocations of both chromosomal segments 12q13-->qter, from one chromosome 12 to 7q32 and from the homologous chromosome 12 to 16q22. The remaining parts of the two chromosomes 12 formed a dicentric chromosome. This is the second reported chondroma with a 12q13-15 rearrangement, and changes of this chromosome region consequently seem to be nonrandom occurrences in chondromas.

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