The "trap" hypothesis of venous ulceration
- PMID: 7682272
- DOI: 10.1016/0140-6736(93)91085-z
The "trap" hypothesis of venous ulceration
Abstract
The pathogenesis of venous ulceration is unknown. We propose that macromolecules leaking into the dermis as a result of venous hypertension bind to or "trap" growth factors and matrix material, which then become unavailable for tissue repair and for the maintenance of tissue integrity.
Comment in
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A rejected letter to the editors of the Lancet and the need for angiologists to prove their usefulness.Vasa. 1993;22(4):361-3. Vasa. 1993. PMID: 7508666 No abstract available.
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Venous ulceration.Lancet. 1993 Jun 5;341(8858):1472. Lancet. 1993. PMID: 8099158 No abstract available.
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Venous ulceration.Lancet. 1993 Jun 5;341(8858):1472-3. Lancet. 1993. PMID: 8099159 No abstract available.
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Venous ulceration.Lancet. 1993 Jul 10;342(8863):121-2. doi: 10.1016/0140-6736(93)91328-j. Lancet. 1993. PMID: 8100893 No abstract available.
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