Review
Immune mechanisms in the sequential steps of metastasis
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- PMID: 7683497
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Review
Immune mechanisms in the sequential steps of metastasis
Crit Rev Oncog.
1993.
Abstract
The number of viable disseminating cancer cells may be reduced dramatically at each step of the metastatic sequence. Host defense mechanisms may contribute to the reduction in the number of cancer cells able to accomplish each step of metastasis. However, augmentation by host defense mechanisms of the ability to complete metastatic events has been observed. The role of cellular host defense mechanisms in the elimination of disseminating cancer cells at individual steps of metastasis is reviewed.
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