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Review
. 1993;4(3):293-311.

Immune mechanisms in the sequential steps of metastasis

F R Miller  1
Affiliations
  • PMID: 7683497
Review

Immune mechanisms in the sequential steps of metastasis

F R Miller. Crit Rev Oncog. 1993.

Abstract

The number of viable disseminating cancer cells may be reduced dramatically at each step of the metastatic sequence. Host defense mechanisms may contribute to the reduction in the number of cancer cells able to accomplish each step of metastasis. However, augmentation by host defense mechanisms of the ability to complete metastatic events has been observed. The role of cellular host defense mechanisms in the elimination of disseminating cancer cells at individual steps of metastasis is reviewed.

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