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. 1993 May 11;21(9):2217-21.
doi: 10.1093/nar/21.9.2217.

The exon trapping assay partly discriminates against alternatively spliced exons

A Andreadis  1 , P E Nisson, K S Kosik, P C Watkins
Affiliations
Free PMC article

The exon trapping assay partly discriminates against alternatively spliced exons

A Andreadis et al. Nucleic Acids Res. .
Free PMC article

Abstract

A cosmid containing eight exons of the gene coding for the microtubule-associated tau protein was subjected to the exon trapping assay. All the constitutive exons contained in the cosmid (4, 5, 7 and 9) were efficiently captured regardless of size. Of the four alternatively spliced exons, three (3, 4A and 8) were not isolated by the assay, but the behavior of exon 6 depended on the identity of its flanking exons.

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References

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