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Case Reports
. 1993 Apr;6(4):255-6.
doi: 10.1002/gcc.2870060414.

A second case of trisomy 8 in Philadelphia chromosome (Ph)-negative cells during the course of Ph-positive chronic myelocytic leukemia

C Bilhou-Nabera, G Marit, I Devianne, F Viard, S Salzes, M Montastruc, M Renoux, A Broustet, J Reiffers, P Bernard
Case Reports

A second case of trisomy 8 in Philadelphia chromosome (Ph)-negative cells during the course of Ph-positive chronic myelocytic leukemia

C Bilhou-Nabera et al. Genes Chromosomes Cancer. 1993 Apr.

Abstract

A Ph-positive CML patient who had received a peripheral blood stem cell autograft in chronic phase demonstrated a transient regression of the Ph-positive clone with the concurrent appearance of another clone with trisomy 8. This latter clone disappeared when the patient received alpha-interferon.

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