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. 1993 Jun;25(3):2381-5.

Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506

S Takaya  1 , O Bronsther, K Abu-Elmagd, H Ramos, J J Fung, S Todo, T E Starzl
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Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506

S Takaya et al. Transplant Proc. 1993 Jun.
No abstract available

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Figures

Fig 1
Fig 1
Dose of intravenous and oral FK 506, plasma trough levels, and serum creatinine levels in patients surviving 30 days (excluding hemodialysis patients). The mean dose of group 1 was significantly higher than those of group 2 or group 3 (P < .001). The mean FK 506 plasma level of group 1 for the first 30 days was significantly higher than those of group 2 or group 3 (P < .001). No statistically significant difference was observed in the dosage of intravenous and oral FK 506 regimens or plasma FK 506 trough levels between group 2 and group 3. The mean values of serum creatinine in group 3 were significantly lower than those of group 1 patients at the second (P = .22), third (P = .0046), and fourth postoperative weeks (P = .0004). Values are expressed as means ± SE.
Fig 2
Fig 2
Division of blood usage during liver transplantation in group 2 (n = 23) and group 3 (n = 19) with low transfusion group [<15 units of packed red blood cells (PRBC)] and high transfusion group (≥15 units of PRBC) (n = 6 in group 2, n = 16 in group 3, excluding hemodialysis patients). In the lower transfusion group, the mean creatinine in group 3 was significantly lower than that of group 2 for the first 30 days (1.48 ± 0.08 mg/dL vs 1.20 ± 0.05 mg/dL, P = .0087). Values are expressed as mean ± SE.
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References

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    1. Todo S, Fung JJ, Starzl TE, et al. Ann Surg. 1990;212:295. - PMC - PubMed
    1. Takaya S, Bronsther O, Iwaki Y, et al. Transplantation. 1992;53:400. - PMC - PubMed
    1. Takaya S, Iwaki Y, Starzl TE. Transplantation. 1992;54:927. - PMC - PubMed
    1. Tamura K, Kobayashi M, Hashimoto K, et al. Transplant Proc. 1987;19 Suppl 6:23. - PubMed

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