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Comparative Study
. 1993 Aug 23;329(1-2):134-8.
doi: 10.1016/0014-5793(93)80209-d.

Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta

M Biel  1 , W Altenhofen, R Hullin, J Ludwig, M Freichel, V Flockerzi, N Dascal, U B Kaupp, F Hofmann
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Free article
Comparative Study

Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta

M Biel et al. FEBS Lett. .
Free article

Abstract

Sequences specific for cyclic nucleotide-gated channels (CNG channels) have been amplified by PCR from cDNA of heart, aorta, sino-atrial node, cerebellum, C-cells and kidney. The complete amino acid sequence of a CNG channel from rabbit aorta has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CNG channel in Xenopus oocytes.

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