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. 1993 Dec;67(12):7677-9.
doi: 10.1128/JVI.67.12.7677-7679.1993.

Characterization of a unique retroviral recombinant containing 7S L sequences

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Characterization of a unique retroviral recombinant containing 7S L sequences

A M Hajjar et al. J Virol. 1993 Dec.

Abstract

Using a recently described system to generate recombinants between avian leukosis viruses (ALV) and cellular neo mRNA (A.M. Hajjar and M.L. Linial, J. Virol. 67:3845-3853, 1993), we isolated a recombinant containing 7S L sequences. Analysis of this recombinant revealed that it most likely arose during reverse transcription of three copackaged RNAs: 7S L RNA, neo RNA, and ALV genomic RNA. Reverse transcription appears to have initiated on the 7S L RNA. A model for the generation of this recombinant is described.

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