Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Feb;79(2):129-34.
doi: 10.1136/bjo.79.2.129.

Detection of glaucomatous damage in patients with osteo-odontokeratoprosthesis

Affiliations

Detection of glaucomatous damage in patients with osteo-odontokeratoprosthesis

G C Falcinelli et al. Br J Ophthalmol. 1995 Feb.

Abstract

Background: Osteo-odontokeratoprosthesis (OOKP) is an autologous transplantation procedure in which the cornea is replaced by an optical cylinder glued to a biological support. Patients undergoing OOKP surgery may develop a secondary glaucoma whose diagnosis, by means of standard diagnostic procedures, is often doubtful.

Methods: In the present study pattern electroretinograms (PERGs), visual evoked potentials (VEPs), contrast sensitivity, and automated threshold perimetry (Humphrey 30-2) were evaluated in 19 OOKP treated patients with postoperative visual acuities > or = 0.8. Nine patients had had a preoperative secondary glaucoma, while the remaining 10 had no history of glaucoma and normal posterior pole.

Results: Results were compared with those obtained from either normal control subjects or from ordinary glaucoma patients. PERG amplitudes and contrast and perimetric sensitivities were reduced in both groups of OOKP patients when compared with normal controls. However, these losses were significantly greater in OOKP patients with glaucoma compared with those with normal posterior pole. VEPs were reduced, compared with controls, only in OOKP patients with glaucoma. These VEP losses were similar to those found in ordinary glaucoma patients.

Conclusion: Among the tests employed, VEPs showed the best accuracy (79%) in discriminating between glaucomatous and non-glaucomatous OOKP treated eyes. The present results suggest a possible use of the VEP technique for detecting glaucomatous dysfunction after OOKP.

PubMed Disclaimer

References

    1. Ber Zusammenkunft Dtsch Ophthalmol Ges. 1972;71:322-35 - PubMed
    1. Ophthalmology. 1985 Dec;92(12):1654-6 - PubMed
    1. Brain. 1986 Jun;109 ( Pt 3):469-90 - PubMed
    1. Am J Ophthalmol. 1993 May 15;115(5):592-6 - PubMed
    1. Exp Eye Res. 1988 Feb;46(2):173-84 - PubMed