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. 1975 Nov;152(2):243-54.
doi: 10.1042/bj1520243.

Analysis of enzyme induction in bacteria

R Young, H Bremer

Analysis of enzyme induction in bacteria

R Young et al. Biochem J. 1975 Nov.

Abstract

The theoretical relations between the induced initiation and accumulation of lac mRNA and its translation are derived, taking the kinetics of repressor-operator dissociation and enzyme maturation into account. These relations are used to evaluate observed data on lac induction and to estimate a number of parameters that characterize the transcription and translation of the beta-galactosidase gene in the bacterium Escherichia coli B/r growing at three different rates (0.7-2.1 doublings/h).

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