Oxytocin induction of labor: a comparison of 20- and 60-min dose increment levels

Abstract

Objectives: To compare the efficacy and complications of oxytocin dose increments at 20- and 60-min intervals for induction of labor in women with low parity.

Methods: One hundred women of low parity requiring induction of labor were randomly allocated to 20- and 60-min oxytocin dose increments, 50 patients in each group. The basal oxytocin dose was 1 milliunit/min and doubling of the oxytocin dose was done at intervals of 20 and 60 min.

Results: The group with 60-min increments had a decreased incidence of uterine hyperstimulation, cesarean section and operative vaginal delivery. The induction-delivery interval was similar in both groups.

Conclusion: The oxytocin infusion regimen with increments at 60-min intervals is safer than and equally effective as 20-min incremental intervals.