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Clinical Trial
. 1976;11(1):25-31.

Mianserin versus amitriptyline. A double-blind-trial evaluated by the AMP system

H P Vogel, D Bente, J Feder, H Helmchen, B Müller-Oerlinghausen, N Bohacek, M Mihovilović, A Brändli, J Fleischhauer, W Walcher
  • PMID: 770364
Clinical Trial

Mianserin versus amitriptyline. A double-blind-trial evaluated by the AMP system

H P Vogel et al. Int Pharmacopsychiatry. 1976.

Abstract

Amitriptyline and mianserin were compared in a double-blind trial. Most of the depressive symptoms were influenced by both drugs, though quantitative and qualitative differences became evident. Amitriptyline predominantly influenced anxiety, despair and suicidal tendencies, while mianserin was particularly effective in psychomotor inhibition and the reduction of vegitative complaints. Mianserin did not show anticholinergic side effects.

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