Avoiding missed opportunities for immunization in the Central African Republic: potential impact on vaccination coverage
- PMID: 7704925
- PMCID: PMC2486578
Avoiding missed opportunities for immunization in the Central African Republic: potential impact on vaccination coverage
Abstract
Quantified in the study are the extent of missed opportunities for immunization and the potential increases in vaccination coverage and timeliness that could be achieved by using all health centre visits to administer childhood vaccinations in the Central African Republic. The data were collected during a national vaccination coverage survey of 642 children aged 12-23 months from three areas: rural, urban, and the capital, Bangui. Dates of all vaccination visits and other health centre visits were obtained from combined vaccination/health cards. Nationwide, 70% of all opportunities for valid measles vaccination were missed. Of these, 28% occurred at visits when at least one vaccine was given, while 72% occurred at other health centre visits. If there had been no missed opportunities to administer all vaccinations due when at least one vaccine was given, the coverage would have increased from 53% to 67% for the diphtheria-pertussis-tetanus series, from 54% to 70% for measles, and from 34% to 59% for all antigens. If there had been no missed opportunities at any visit, the corresponding increases would have been to 70%, 76%, and 65%. For measles, 46% of the potential increase depends on recognizing that an earlier dose of the vaccine was invalid and on revaccinating. Days-at-risk for measles (after the age of 270 days) would have been reduced by a mean of 74 days per subject with a health card had no opportunities been missed. The method used serves as a valuable adjunct to evaluations of missed opportunities based on exit interviews at health facilities.(ABSTRACT TRUNCATED AT 250 WORDS)
PIP: The Central African Republic in 1986 initiated an accelerated immunization program which became fully operational in 1988. As part of the program, a policy of vaccinating eligible children at all health facility contacts was adopted. National surveys conducted in 1985 and 1989 indicated that there had been a substantial increase in vaccination coverage, but that immunizations were not being given at all visits on a widespread basis. The authors quantify the extent of these missed opportunities for immunization and the potential increases in vaccination coverage and timeliness which could be achieved if all health center visits were used to administer childhood vaccinations in the Central Africa Republic. Study data were collected during a national vaccination coverage survey of 642 children aged 12-23 months from rural and urban areas as well as Bangui, the capital. Dates of all vaccination and other health center visits were obtained from combined vaccination/health cards. Analysis found that 70% of all opportunities nationwide for valid measles vaccination were missed. Of these, 28% occurred at visits when at least one vaccine was given and 72% occurred at other health center visits. If there had been no missed opportunities to administer all vaccinations due when at least one vaccine was given, coverage would have increased from 53% to 67% for the diphtheria-pertussis-tetanus series, from 54% to 70% for measles, and from 34% to 59% for all antigens. If there had been no missed opportunities at any visit, the corresponding increases would have been 70%, 76%, and 65%, respectively. For measles, 46% of the potential increase depends on recognizing that an earlier dose of the vaccine was invalid and on revaccinating. Days at risk for measles after the age of 270 days would have been reduced by a mean of 74 days per subject with an health card had no opportunities been missed.
Similar articles
-
The contribution of missed opportunities to childhood underimmunization in Baltimore.Pediatrics. 1996 Apr;97(4):474-80. Pediatrics. 1996. PMID: 8632931
-
Immunization opportunities missed among urban poor children.Pediatrics. 1992 Jun;89(6 Pt 1):1019-26. Pediatrics. 1992. PMID: 1594341
-
Would better adherence to guidelines improve childhood immunization rates?Pediatrics. 1996 Dec;98(6 Pt 1):1062-8. Pediatrics. 1996. PMID: 8951254
-
Two-dose measles vaccination schedules.Bull World Health Organ. 1993;71(3-4):421-8. Bull World Health Organ. 1993. PMID: 8324862 Free PMC article. Review.
-
Principles of measles control.Bull World Health Organ. 1991;69(1):1-7. Bull World Health Organ. 1991. PMID: 2054914 Free PMC article. Review.
Cited by
-
Monitoring the performance of the Expanded Program on Immunization: the case of Burkina Faso.BMC Int Health Hum Rights. 2009 Oct 14;9 Suppl 1(Suppl 1):S12. doi: 10.1186/1472-698X-9-S1-S12. BMC Int Health Hum Rights. 2009. PMID: 19828056 Free PMC article.
-
Timeliness of routine childhood vaccination in 103 low-and middle-income countries, 1978-2021: A scoping review to map measurement and methodological gaps.PLOS Glob Public Health. 2022 Jul 14;2(7):e0000325. doi: 10.1371/journal.pgph.0000325. eCollection 2022. PLOS Glob Public Health. 2022. PMID: 36962319 Free PMC article.
-
Prevalence of missed opportunities for measles immunization in rural areas of Gujarat.Indian J Pediatr. 2001 Jul;68(7):609-12. doi: 10.1007/BF02752272. Indian J Pediatr. 2001. PMID: 11519283
-
Timely vaccination with valid doses in a high coverage country, Oman.BMC Public Health. 2025 May 9;25(1):1710. doi: 10.1186/s12889-025-22920-z. BMC Public Health. 2025. PMID: 40346509 Free PMC article.
-
Missed Opportunities for Measles, Mumps, and Rubella (MMR) Immunization in Mesoamerica: Potential Impact on Coverage and Days at Risk.PLoS One. 2015 Oct 27;10(10):e0139680. doi: 10.1371/journal.pone.0139680. eCollection 2015. PLoS One. 2015. PMID: 26506563 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials