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Review
. 1994 Dec;102 Suppl 10(Suppl 10):179-84.
doi: 10.1289/ehp.94102s10179.

Ozone, NO, and NO2: oxidant air pollutants and more

J A Last  1 , W M Sun, H Witschi
Affiliations
Review

Ozone, NO, and NO2: oxidant air pollutants and more

J A Last et al. Environ Health Perspect. 1994 Dec.

Abstract

This article reviews the acute and chronic toxicity of the three oxidant air pollutants ozone, nitric oxide (NO), and nitrogen dioxide (NO2). The toxicity of binary mixtures of NO2 with other inhaled agents is also discussed. Newer studies are emphasized, especially those published in the last 5 years or still in press. Very recent data from our laboratory that suggest a new cellular mechanism of importance in lung injury in animals exposed to mixtures of ozone and NO2 that may have general relevance with regard to the effects of oxidant air pollutants on the lung are also presented.

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