Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia
- PMID: 7706521
- PMCID: PMC502264
- DOI: 10.1136/jcp.48.1.59
Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia
Abstract
Aims: To evaluate the interobserver variation in the diagnosis of cervical intraepithelial lesions, including the new category "borderline abnormalities of uncertain significance" (BAUS) which has not been tested before.
Methods: Biopsy specimens of 122 patients were reviewed by five histopathologists and the diagnoses subjected to kappa statistical analysis.
Results: There was poor interobserver agreement in all categories, particularly between BAUS and normal tissue.
Conclusions: The current guidelines for the histological diagnosis of cervical intraepithelial neoplasia and BAUS are poorly reproducible.
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