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. 1995 May;69(5):3201-5.
doi: 10.1128/JVI.69.5.3201-3205.1995.

Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro

C Bonne-Andrea  1 , S Santucci, P Clertant
Affiliations

Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro

C Bonne-Andrea et al. J Virol. 1995 May.

Abstract

Bovine papillomavirus E1 protein was found to be as efficient as the simian virus 40 large T antigen in initiating DNA synthesis in a cell-free system derived from COS1 cells. Multiple rounds of DNA synthesis occur, initiated at the bovine papillomavirus type 1 origin. Therefore, E1 functions in vitro as a lytic virus initiator.

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