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Review
. 1995 Jan;37(1):3-12.
doi: 10.1007/BF00588511.

Review of the embryologic development of the pituitary gland and report of a case of hypophyseal duplication detected by MRI

S S Kollias  1 , W S Ball, E C Prenger
Affiliations
Review

Review of the embryologic development of the pituitary gland and report of a case of hypophyseal duplication detected by MRI

S S Kollias et al. Neuroradiology. 1995 Jan.

Abstract

We describe the clinical manifestations, associated abnormalities, MRI appearances and pathologic significance of a case of hypophyseal duplication. A 16-year-old girl presented with delayed sexual development and history of midline craniofacial anomalies. MRI revealed paired infundibula extending inferiorly to two small pituitary glands, a midline hypothalamic mass, and a midline cleft in the basisphenoid. Twelve cases of pituitary duplication have previously been described. The suggested pathogenesis is duplication of the prechordal plate and anterior end of the notochord during early embryologic development.

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