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Case Reports
. 1995 Apr;119(4):516-7.
doi: 10.1016/s0002-9394(14)71242-5.

Treatment of progressive outer retinal necrosis with sorivudine

M K Pinnolis  1 , D Foxworthy, B Kemp
Affiliations
Case Reports

Treatment of progressive outer retinal necrosis with sorivudine

M K Pinnolis et al. Am J Ophthalmol. 1995 Apr.

Abstract

Purpose/methods: We examined a patient with progressive outer retinal necrosis, which is presumably caused by the varicella-zoster virus in patients with the acquired immunodeficiency syndrome.

Results/conclusions: The patient was successfully treated with a combination of intravitreal ganciclovir and oral sorivudine. Treatment for progressive outer retinal necrosis has been disappointing; both acyclovir and ganciclovir have had only limited success. Sorivudine, a new antiviral medication with activity against varicella-zoster virus, may represent an effective alternative treatment for retinal necrosis.

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