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Review
. 1994 Dec;6(6):931-7.
doi: 10.1016/0952-7915(94)90016-7.

Autoantibodies in scleroderma and tightskin mice

C Bona  1 , N Rothfield
Affiliations
Review

Autoantibodies in scleroderma and tightskin mice

C Bona et al. Curr Opin Immunol. 1994 Dec.

Abstract

There is much evidence to suggest that scleroderma in human patients is caused by a fundamental defect in the immune system. In tightskin mice, the scleroderma syndrome is associated with autoimmunity, particularly autoantibodies interacting with scleroderma target antigens.

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