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Case Reports
. 1977 Dec;68(6):578-81.

Fulminant hepatic failure associated with methyldopa

  • PMID: 77129
Case Reports

Fulminant hepatic failure associated with methyldopa

A R Puppala et al. Am J Gastroenterol. 1977 Dec.

Abstract

A patient with fatal submassive hepatic necrosis after methyldopa is described. Patient had positive L.E. cell preparation. The literature and the two previous cases of submassive hepatic necrosis were briefly reviewed. Methyldopa occasionally produces severe hepatitis, chronic active and rarely submassive necrosis.

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