Fulminant hepatic failure associated with methyldopa
- PMID: 77129
Fulminant hepatic failure associated with methyldopa
Abstract
A patient with fatal submassive hepatic necrosis after methyldopa is described. Patient had positive L.E. cell preparation. The literature and the two previous cases of submassive hepatic necrosis were briefly reviewed. Methyldopa occasionally produces severe hepatitis, chronic active and rarely submassive necrosis.