Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1995 Jan;72(1):56-7.
doi: 10.1136/adc.72.1.56.

Transient neonatal diabetes and later onset diabetes: a case of inherited insulin resistance

J P Shield  1 , J D Baum
Affiliations
Case Reports

Transient neonatal diabetes and later onset diabetes: a case of inherited insulin resistance

J P Shield et al. Arch Dis Child. 1995 Jan.

Abstract

A 13 year old girl who had had transient neonatal diabetes developed permanent diabetes. She had raised fasting insulin concentrations suggestive of insulin resistance with a suboptimal insulin response to glucose loading. Both her mother and sister had profound insulin resistance; neither had clinical diabetes. This is the first time inherited insulin resistance has been implicated in the pathogenesis of permanent diabetes developing after transient neonatal diabetes.

PubMed Disclaimer

References

    1. Arch Dis Child. 1966 Jun;41(217):279-85 - PubMed
    1. Adv Pediatr. 1969;16:345-63 - PubMed
    1. Nat Genet. 1994 May;7(1):10 - PubMed
    1. Diabetes Care. 1992 Oct;15(10):1273-6 - PubMed
    1. J Pediatr. 1993 Apr;122(4):598-600 - PubMed

Publication types