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Comparative Study
. 1994 Oct;16(5):374-7.

[Evaluation of two glycolipids from M. tuberculosis in the serodiagnosis of tuberculosis]

[Article in Chinese]
W Hou  1 , Q Wu, P Zhang
Affiliations
  • PMID: 7720130
Comparative Study

[Evaluation of two glycolipids from M. tuberculosis in the serodiagnosis of tuberculosis]

[Article in Chinese]
W Hou et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1994 Oct.

Abstract

Sera from 112 healthy controls and 120 pulmonary tuberculous patients (61 untreated patients and 59 active patients) were assayed, by ELISA, to test the activity of IgG and IgM antibodies against antigen of 2, 3-diacyl-trehalose-2'-sulphate (SL IV) a phenolglycolipid antigen (PGLTb1) and purified protein derivative (PPD) from M. tuberculosis. Respectively, for SL IV-IgG-ELISA, SL IV-IgM-ELISA, PGLTb1-IgG-ELISA, PGLTb1-IgM-ELISA, PPD-IgG-ELISA, the specificities were of 96.43, 96.43, 96.43, 96.43 and 95.53%; the sensitivities were of 51.67, 32.50, 14.17, 18.33 and 33.33%; the efficiencies were of 73.28, 63.36, 53.88, 56.03 and 62.93%; the predictive values for a positive result were of 96.87, 86.67, 80.95, 84.62 and 88.64%. Among the three antigens tested, SL IV was found to be better than PGLTb1 and PPD.

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