Physical performance does not improve in elderly patients following successful kidney transplantation

Abstract

In a prospective study before, and during 1 year following, kidney transplantation, physical strength and performance were tested in patients over the age of 60 and in younger control patients. Quadriceps strength increased significantly in the control patients (+3.3 +/- 3.2 kg, n = 11, P = 0.007) but remained stable in the successfully grafted elderly patients (-0.1 +/- 4.2 kg, n = 16). Grip strength tended to increase in the control patients (P = 0.064) but not in the elderly. Stepping up on a chair--a test of strength and coordination in combination--could be performed by all control patients on all occasions. Fourteen of 16 elderly patients managed it before transplant, but only 3/12 after 3 weeks, 5/13 after 6 months, and 10/16 after 1 year. Forced expiratory volume during 1 s and working capacity on the ergometer bicycle also tended to decline during 1 year. We conclude that the average elderly person does not gain strength during 1 year after successful kidney transplantation.