Detection of interleukin-6 and prostaglandin E2 in bronchoalveolar lavage fluids of pigs experimentally infected with Mycoplasma hyponeumoniae

Abstract

In this study, interleukin-6 (IL-6) and prostaglandin E2 (PGE2) were detected in the bronchoalveolar lavage fluids (BALF) from pigs experimentally infected with Mycoplasma hyopneumoniae. IL-6 was detected at 2 weeks post-inoculation (PI), and significantly increased levels of PGE2 were observed at 4 weeks PI. In the BALF collected from infected pigs at 4 weeks PI, the levels of IL-6 increased significantly in the pigs with pneumonic lesions. However, increased levels of PGE2 were observed in all the infected pigs.