Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Oct;38(5):247-50.

Transduction of imipenem resistance by the phage F-116 from a nosocomial strain of Pseudomonas aeruginosa isolated in Slovakia

J Blahová  1 , M Hupková, K Králiková, V Krcméry
Affiliations
  • PMID: 7725997

Transduction of imipenem resistance by the phage F-116 from a nosocomial strain of Pseudomonas aeruginosa isolated in Slovakia

J Blahová et al. Acta Virol. 1994 Oct.

Abstract

Generalized transducting Pseudomonas aeruginosa phage F-116 was propagated in an Imipenem (IMI)-resistant clinical isolate of P. aeruginosa No. 191 and the phage was then used to transduce the IMI-resistance to a susceptible auxotrophic mutant strain of the same species. Transduction seems to be a suitable method for study of resistance determinant(s) and mechanism of resistance in this important species. It was found that the IMI-resistance of the clinical strain No. 191 is caused by production of a betalactamase specifically hydrolyzing this antibiotic.

PubMed Disclaimer

MeSH terms