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. 1995 Feb;39(2):561-3.
doi: 10.1128/AAC.39.2.561.

DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae

T Deguchi  1 , M Yasuda, M Asano, K Tada, H Iwata, H Komeda, T Ezaki, I Saito, Y Kawada
Affiliations

DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae

T Deguchi et al. Antimicrob Agents Chemother. 1995 Feb.

Abstract

Eight quinolone-resistant clinical isolates of Neisseria gonorrhoeae were shown to carry mutations in their GyrA proteins. Six isolates had a single amino acid change of serine to phenylalanine at the position corresponding to Ser-83 in Escherichia coli. In addition to the change of serine to phenylalanine, two isolates had another change of aspartic acid to asparagine at the position corresponding to Asp-87 in E. coli.

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References

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