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. 1994 Jul;5(7):416-23.
doi: 10.1007/BF00357001.

Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence

C Rougeulle  1 , L Colleaux, B Dujon, P Avner
Affiliations

Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence

C Rougeulle et al. Mamm Genome. 1994 Jul.

Erratum in

  • Mamm Genome 1994 Dec;5(12):836

Abstract

The Xist sequence has several characteristics that make it a potential candidate for the X-inactivation center. To investigate the role of Xist and adjacent sequences lying within the X-inactivation center candidate region, a 460-kb region surrounding the murine Xist sequence has been arrayed in lambda contigs with a combination of IRS-PCR-based hybridization and YAC fragmentation. The orientation of the Xist sequence in relation to the telomere and centromere of the X Chromosome (Chr) has been established with this contig and shown to be inverted compared to that in human.

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