Direct sequencing of PCR amplified pig PrP genes
- PMID: 7727546
- DOI: 10.1016/0925-4439(95)00041-2
Direct sequencing of PCR amplified pig PrP genes
Abstract
The protein coding regions of the PrP genes of six pigs were sequenced directly from PCR-amplified genomic DNA. All six sequences were identical. The gene encodes a protein of 257 amino acids and shows an overall similarity of 77 to 88% with the PrP sequences from other mammalian species. The significance of amino acids unique to the pig PrP are discussed.
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