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Case Reports
. 1976 Apr;130(4):433-6.
doi: 10.1001/archpedi.1976.02120050091018.

Fatal disseminated BCG infection. An investigation of the immunodeficiency

J Passwell, D Katz, Y Frank, Z Spirer, B E Cohen, M Ziprkowski
Case Reports

Fatal disseminated BCG infection. An investigation of the immunodeficiency

J Passwell et al. Am J Dis Child. 1976 Apr.

Abstract

A 2-year-old boy had a fatal disseminated BCG infection. Immunologic assessment showed a normal humoral response and normal numbers of E rosettes, normal thymus weight and histological features, but an abnormal response of lymphocytes in vitro and negative skin tests. Histological examination showed the presence of Gram-negative acid-fast bacilli within the macrophages. The possible mechanisms of immunodeficiency in this patient are discussed.

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