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. 1976 Feb;9(2):347-9.
doi: 10.1128/AAC.9.2.347.

Synergy in the antimicrobial action of penicillin and beta-chloro-D-alanine in vitro

T S Soper, J M Manning

Synergy in the antimicrobial action of penicillin and beta-chloro-D-alanine in vitro

T S Soper et al. Antimicrob Agents Chemother. 1976 Feb.

Abstract

beta-Chloro-d-alanine and penicillin G acted on early and late steps, respectively, in the biosynthesis of the bacterial cell wall. In combination these compounds showed a synergistic effect on the growth of Salmonella typhimurium and of Escherichia coli in vitro.

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