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. 1995 Apr 15;307 ( Pt 2)(Pt 2):327-30.
doi: 10.1042/bj3070327.

Translation in vivo of 5' untranslated-region splice variants of human surfactant protein-A

A M Karinch  1 , J Floros
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Translation in vivo of 5' untranslated-region splice variants of human surfactant protein-A

A M Karinch et al. Biochem J. .

Abstract

Transcripts of human SP-A genes, SP-A1 and SP-A2, undergo alternative splicing of 5' untranslated-region exons. We reverse-transcribed and amplified free cytoplasmic and polysome-bound RNA and showed that (a) all splice variants of both genes are translated in vivo, (b) the relative translatability of splice variants can differ among individuals, and (c) the relative levels of different SP-A splice variants differ among individuals.

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References

    1. Am J Obstet Gynecol. 1984 Jan 1;148(1):48-53 - PubMed
    1. Nature. 1964 Jan 18;201:264-70 - PubMed
    1. J Biol Chem. 1986 Jul 5;261(19):9029-33 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Feb;84(4):1010-4 - PubMed
    1. Biochim Biophys Acta. 1989 Feb 20;1001(3):294-301 - PubMed

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