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. 1994 Aug-Oct;28(4-5):267-71.
doi: 10.3109/03005369409086576.

Contralateral suppression of transient evoked otoacoustic emissions in guinea-pigs: effects of gentamicin

J M Aran  1 , J P Erre, P Avan
Affiliations

Contralateral suppression of transient evoked otoacoustic emissions in guinea-pigs: effects of gentamicin

J M Aran et al. Br J Audiol. 1994 Aug-Oct.

Abstract

A single injection of gentamicin in the awake guinea-pig induces a transient blockade of the suppression by contralateral white noise of tone-pip evoked compound action potential (Smith et al., 1994). We report here the reversible blockade, in exactly the same experimental conditions, of the suppression of click-evoked otoacoustic emissions. These observations confirm the transient action of gentamicin at the medial efferent/outer hair cell synapse, likely via the reversible blockade of calcium channels observed in vitro (Dulon et al., 1989).

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