Recombining the structures of HIV integrase, RuvC and RNase H
- PMID: 7735828
- DOI: 10.1016/s0969-2126(01)00142-3
Recombining the structures of HIV integrase, RuvC and RNase H
Abstract
The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.
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