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Comparative Study
. 1995 Apr 18;14(8):1812-8.
doi: 10.1002/j.1460-2075.1995.tb07169.x.

Sequence-dependent bending propensity of DNA as revealed by DNase I: parameters for trinucleotides

I Brukner  1 , R Sánchez, D Suck, S Pongor
Affiliations
Comparative Study

Sequence-dependent bending propensity of DNA as revealed by DNase I: parameters for trinucleotides

I Brukner et al. EMBO J. .

Abstract

Structural parameters characterizing the bending propensity of trinucleotides were deduced from DNase I digestion data using simple probabilistic models. In contrast to dinucleotide-based models of DNA bending and/or bendability, the trinucleotide parameters are in good agreement with X-ray crystallographic data on bent DNA. This improvement may be due to the fact that the trinucleotide model incorporates more sequence context information than do dinucleotide-based descriptions.

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References

    1. J Mol Biol. 1994 Feb 11;236(1):26-32 - PubMed
    1. Biochemistry. 1993 Aug 31;32(34):8923-31 - PubMed
    1. Nature. 1994 Feb 24;367(6465):754-7 - PubMed
    1. Nature. 1994 Mar 31;368(6470):469-73 - PubMed
    1. EMBO J. 1994 Oct 17;13(20):4983-90 - PubMed

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