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Review
. 1976 Apr;17(4):273-9.
doi: 10.1136/gut.17.4.273.

Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man

S G Hamilton, H J Sheiner, M F Quinlan
Review

Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man

S G Hamilton et al. Gut. 1976 Apr.

Abstract

By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the overall rate of gastric emptying. Fundal motility was unaffected though reflux from the antrum occurred.

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References

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