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Review
. 1976 Apr;17(4):280-4.
doi: 10.1136/gut.17.4.280.

Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis

J A Dodge, A A Karim
Review

Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis

J A Dodge et al. Gut. 1976 Apr.

Abstract

Administration of pentagastrin in depot form to 20 pregnant bitches produced pyloric hypertrophy in about 28% and gastroduodenal ulceration in about 16% of their pups. The two lesions were not necessarily found in the same individuals. Histological appearances of the pylorus in affected pups closely resembled those of human infantile pyloric stenosis.

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References

    1. Arch Dis Child. 1974 Oct;49(10):796-801 - PubMed
    1. Gut. 1969 Sep;10(9):723-9 - PubMed
    1. Surgery. 1970 Feb;67(2):360-3 - PubMed
    1. Nature. 1970 Jan 17;225(5229):284-5 - PubMed
    1. Am J Physiol. 1969 Jul;217(1):251-4 - PubMed

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