Coexistence of human immunodeficiency virus infection and systemic lupus erythematosus
- PMID: 7738963
Coexistence of human immunodeficiency virus infection and systemic lupus erythematosus
Abstract
A variety of rheumatic disorders has been reported during the course of human immunodeficiency virus (HIV) infection; however, its association with systemic lupus erythematosus (SLE) is extremely rare. The effect of HIV infection on CD4 lymphocytes may ameliorate SLE activity and spur remission. We observed 2 patients with SLE who later developed HIV infection. Both patients' lupus went into remission, and their course was complicated by aseptic necrosis of the bone. These findings suggest that HIV infection may have an important effect on the natural course of SLE and may also have a pathogenic role in avascular necrosis.
Comment in
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Development of acquired immune deficiency syndrome in a patient with systemic lupus erythematosus.J Rheumatol. 1996 Jul;23(7):1308. J Rheumatol. 1996. PMID: 8823717 No abstract available.
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Diagnostic approach to possible HIV-1 infection in patients with systemic lupus erythematosus.J Rheumatol. 1997 Apr;24(4):807-8. J Rheumatol. 1997. PMID: 9101527 No abstract available.
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