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Case Reports
. 1995 Feb;9(1):11-5.
doi: 10.1007/BF00858956.

Inherited factor H deficiency and collagen type III glomerulopathy

B A Vogt  1 , R J Wyatt, B A Burke, S C Simonton, C E Kashtan
Affiliations
Case Reports

Inherited factor H deficiency and collagen type III glomerulopathy

B A Vogt et al. Pediatr Nephrol. 1995 Feb.

Abstract

A non-immune complex-mediated glomerulonephritis associated with persistent hypocomplementemia occurred in a young boy. Measurement of complement components revealed complete factor H deficiency, inherited as an autosomal recessive trait. Evaluation of the renal lesion revealed extensive deposition of type III collagen suggestive of collagen type III glomerulopathy, a recently identified cause of chronic renal insufficiency in children and adults. This report represents the first association of inherited factor H deficiency with collagen type III glomerulopathy.

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