Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1993:2:395-401.

The role of calcium homeostasis and calcium currents in ethanol actions on central mammalian neurons

P L Carlen  1 , S S Jahromi, T A Valiante, A A Velumian, J L Weiner, L Zhang
Affiliations
  • PMID: 7748329
Review

The role of calcium homeostasis and calcium currents in ethanol actions on central mammalian neurons

P L Carlen et al. Alcohol Alcohol Suppl. 1993.

Abstract

The ubiquitous role of calcium in ethanol actions measured electrophysiologically in central neurons is discussed. Acute ethanol administration to rat hippocampal neurons in vitro causes a hyperpolarization, increased AHPs, increased EPSPs and IPSPs, decreased modelled electronic interneuronal coupling, decreased high threshold Ca2+ currents, increased Ik, and increased synaptic GABAA currents. Alcohol withdrawal reverses some of these actions. Ca2+ is implicated in all of the above ethanol mediated effects.

PubMed Disclaimer

Publication types

LinkOut - more resources