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. 1995 May 27;345(8961):1339-40.
doi: 10.1016/s0140-6736(95)92538-4.

Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients

P L Rady  1 , A Yen, J L Rollefson, I Orengo, S Bruce, T K Hughes, S K Tyring
Affiliations

Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients

P L Rady et al. Lancet. .

Abstract

Herpesvirus-like DNA sequences (KSHV) have been reported to be associated with various forms of Kaposi's sarcoma (KS). To determine if KSHV was associated with other proliferative skin lesions from non-AIDS immunocompromised patients, 33 skin lesions (basal cell carcinomas, squamous cell carcinomas, actinic keratoses, verruca vulgaris, atypical squamous proliferations, and seborrhoeic keratosis) from 4 organ-transplant patients receiving immunosuppressive therapy were tested for KSHV by PCR. KSHV sequences were detected in 82% of these skin lesions. Our results suggest that KSHV is associated with lesions other than KS in non-AIDS immunocompromised patients, and may also be involved in the pathogenesis of the various forms of proliferative skin lesions from organ-transplant patients.

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  • HHV-8 in lymphoproliferative lesions in skin.
    Sander CA, Simon M, Puchta U, Raffeld M, Kind P. Sander CA, et al. Lancet. 1996 Aug 17;348(9025):475-6. doi: 10.1016/S0140-6736(05)64569-2. Lancet. 1996. PMID: 8709802 No abstract available.

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