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Review
. 1995 Mar;7(2):102-6.
doi: 10.1097/00001622-199503000-00002.

Epstein-Barr virus and bone marrow transplantation

C Caldas  1 , R Ambinder
Affiliations
Review

Epstein-Barr virus and bone marrow transplantation

C Caldas et al. Curr Opin Oncol. 1995 Mar.

Abstract

The development of Epstein-Barr virus-associated posttransplantation lymphoproliferative disease correlates with increased viral burden in lymphocytes. Patterns of viral gene expression in tumors are complex and heterogenous. Conventional chemotherapy for postransplantation lymphoproliferative disease is sometimes associated with long-term disease-free survival. A promising new approach involves adoptive cellular immunotherapy with donor lymphocytes or T-cell lines. Allogeneic bone marrow transplantation has been successful in patients with an inherited lack of immune response to Epstein-Barr virus.

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Comment in

  • Bone marrow transplantation.
    Santos GW. Santos GW. Curr Opin Oncol. 1995 Mar;7(2):101. doi: 10.1097/00001622-199503000-00001. Curr Opin Oncol. 1995. PMID: 7756373 No abstract available.

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