Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Feb 10;25(3):701-6.
doi: 10.1016/0888-7543(95)80013-c.

Chromosomal assignment and genomic structure of Il15

D M Anderson  1 , L Johnson, M B Glaccum, N G Copeland, D J Gilbert, N A Jenkins, V Valentine, M N Kirstein, D N Shapiro, S W Morris, et al.
Affiliations

Chromosomal assignment and genomic structure of Il15

D M Anderson et al. Genomics. .

Abstract

Interleukin-15 (IL-15) is a novel cytokine whose effects on T-cell activation and proliferation are similar to those of interleukin-2 (IL-2), presumably because IL-15 utilizes the beta and gamma chains of the IL-2 receptor. Murine IL-15 cDNA and genomic clones were isolated and characterized. The murine Il15 gene was found to consist of eight exons spanning at least 34 kb and was localized to the central region of mouse chromosome 8 by interspecific backcross analysis. Intron positions in a partial human IL15 genomic clone were identical with positions of corresponding introns in the murine gene. The human IL15 gene was mapped to human chromosome 4q31 by fluorescence in situ hybridization.

PubMed Disclaimer

Publication types

Associated data