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Comparative Study
. 1995 Mar-Apr;15(2):507-10.

Plasma amino acid imbalance in patients with lung and breast cancer

A Cascino  1 , M Muscaritoli, C Cangiano, L Conversano, A Laviano, S Ariemma, M M Meguid, F Rossi Fanelli
Affiliations
  • PMID: 7763031
Comparative Study

Plasma amino acid imbalance in patients with lung and breast cancer

A Cascino et al. Anticancer Res. 1995 Mar-Apr.

Abstract

In order to evaluate whether different solid tumors may specifically influence plasma free amino acid (PFAA) profile, PFAA were analysed in seventy-four patients with lung (41 patients) and breast cancer (33 patients) and 28 healthy subjects. In lung cancer patients a significant reduction of gluconeogenic amino acids, threonine, serine, glycine and a significant increase of free tryptophan and glutamic acid was found. In breast cancer patients a significant increase of ornithine, glutamic acid and free tryptophan was found. The comparison of PFAA profiles between lung and breast cancer suggests that different tumors have a different influence on the host's PFAA pattern.

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