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. 1993 Apr;39(1):16-20.
doi: 10.1007/BF00166841.

Steroid hydroxylation with free and immobilized cells of Penicillium raistrickii in the presence of beta-cyclodextrin

D Schlosser  1 , S Irrgang, H P Schmauder
Affiliations

Steroid hydroxylation with free and immobilized cells of Penicillium raistrickii in the presence of beta-cyclodextrin

D Schlosser et al. Appl Microbiol Biotechnol. 1993 Apr.

Abstract

Free and Ca-alginate-immobilized cells of Penicillium raistrickii i 477 were used for 15 alpha-hydroxylation of 13-ethyl-gon-4-en-3,17-dione. The product formation of both free and immobilized cells was increased in the presence of beta-cyclodextrin, in comparison with reactions carried out in the presence of methanol. Application of beta-cyclodextrin led to increasing solubility of the steroid substrate. The fungus was able to utilize beta-cyclodextrin as a carbon source.

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References

    1. Appl Environ Microbiol. 1983 Feb;45(2):436-43 - PubMed
    1. J Basic Microbiol. 1991;31(5):385-90 - PubMed
    1. J Basic Microbiol. 1991;31(6):453-77 - PubMed

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