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Review
. 1993 Apr;11(4):143-51.
doi: 10.1016/0167-7799(93)90089-R.

Beware of mycoplasmas

S Rottem  1 , M F Barile
Affiliations
Review

Beware of mycoplasmas

S Rottem et al. Trends Biotechnol. 1993 Apr.

Abstract

Mycoplasma infection of cell cultures is widespread and has major detrimental effects on cellular physiology and metabolism. Since cell culture is used extensively, both in research and in industrial production processes, questions of primary concern arise, such as: how can mycoplasma contamination be detected; what are the effects of such contamination on cellular functions; what methods are available for eliminating contamination?

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