Mass spectrometry of proteins and peptides in biotechnology

Abstract

Recent technological developments in the field of mass spectrometry have resulted in enhanced performance in traditional biotechnological applications and are opening up new approaches to a wide range of problems in protein analysis. Developments in the area of interfacing mass spectrometry with high-resolution separation techniques and the observation of non-covalent interactions and protein conformational changes by mass spectrometry represent notable advances in the past year.