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Review
. 1978:24:139-48.
doi: 10.1159/000401510.

African trials in chemotherapy of gastrointestinal cancer

Review

African trials in chemotherapy of gastrointestinal cancer

C L Olweny. Antibiot Chemother (1971). 1978.

Abstract

Bleomycin either alone or in combination with radiotherapy was used in the treatment of 24 patients with non-resectable cancer of the oesophagus. Improvement in performance (swallowing) status was observed in 75% of patients, although only 19% were known to be alive after 1 year of follow-up. Patients with liver cancer were treated with adriamycin. The response rate was dose dependent and was 40% at best. Combination of adriamycin with other drugs did not improve the response rate. Intra-arterial adriamycin appears more efficacious and gave a response rate of 60%.

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